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Altered Prostanoid Metabolism Contributes to Impaired Angiogenesis in Persistent Pulmonary Hypertension of the Newborn

BACKGROUND: PPHN is associated with decreased lung angiogenesis and impaired pulmonary vasodilatation at birth. Prostanoids are important modulators of vascular tone and angiogenesis. We hypothesized that altered levels of prostacyclin (PGI(2)), a potent vasodilator, and thromboxane (TXA(2)), a vaso...

詳細記述

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書誌詳細
出版年:Pediatr Res
主要な著者: Mahajan, Chaitali N., Afolayan, Adeleye J., Eis, Annie, Teng, Ru-Jeng, Konduri, Girija G.
フォーマット: Artigo
言語:Inglês
出版事項: 2014
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4346417/
https://ncbi.nlm.nih.gov/pubmed/25521916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.209
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