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Altered Prostanoid Metabolism Contributes to Impaired Angiogenesis in Persistent Pulmonary Hypertension of the Newborn
BACKGROUND: PPHN is associated with decreased lung angiogenesis and impaired pulmonary vasodilatation at birth. Prostanoids are important modulators of vascular tone and angiogenesis. We hypothesized that altered levels of prostacyclin (PGI(2)), a potent vasodilator, and thromboxane (TXA(2)), a vaso...
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| Publicado no: | Pediatr Res |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4346417/ https://ncbi.nlm.nih.gov/pubmed/25521916 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/pr.2014.209 |
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