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Interaction of endothelial nitric oxide synthase with mitochondria regulates oxidative stress and function in fetal pulmonary artery endothelial cells

An increase in oxygen tension at birth is one of the key signals that initiate pulmonary vasodilation in the fetal lung. We investigated the hypothesis that targeting endothelial nitric oxide synthase (eNOS) to the mitochondrial outer membrane regulates reactive oxygen species (ROS) formation in the...

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Pubblicato in:Am J Physiol Lung Cell Mol Physiol
Autori principali: Konduri, Girija G., Afolayan, Adeleye J., Eis, Annie, Pritchard, Kirkwood A., Teng, Ru-Jeng
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Physiological Society 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4628983/
https://ncbi.nlm.nih.gov/pubmed/26320159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajplung.00386.2014
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