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Nitrotyrosine Impairs Angiogenesis and Uncouples eNOS Activity of Pulmonary Artery Endothelial Cells Isolated from Developing Sheep Lungs

Infection is known to impair the growth of developing lungs. It is known that plasma free nitrotyrosine (NT) levels can reach 150 μM during sepsis. Free NT incorporates into microtubules and impairs cell function. We hypothesize that free NT perturbs the angiogenic activity of pulmonary artery endot...

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Détails bibliographiques
Auteurs principaux: Teng, Ru-Jeng, Wu, Tzong-Jin, Bisig, C. Gaston, Eis, Annie, Pritchard, Kirkwood A., Konduri, Girija G.
Format: Artigo
Langue:Inglês
Publié: 2011
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3086583/
https://ncbi.nlm.nih.gov/pubmed/21057377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1203/PDR.0b013e318204dcb8
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