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A TALE of Two Nucleases: Gene Targeting for the Masses?

Genome editing appears poised to enter an exciting new era. Targeted double-stranded breaks due to custom restriction enzymes are powerful nucleating events for the induction of local changes in the genome. The zinc finger nuclease (ZFN) platform established the potential of this approach for the ze...

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Bibliographic Details
Main Authors: Clark, Karl J., Voytas, Daniel F., Ekker, Stephen C.
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2011
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174730/
https://ncbi.nlm.nih.gov/pubmed/21929364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/zeb.2011.9993
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