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A TALE of Two Nucleases: Gene Targeting for the Masses?

Genome editing appears poised to enter an exciting new era. Targeted double-stranded breaks due to custom restriction enzymes are powerful nucleating events for the induction of local changes in the genome. The zinc finger nuclease (ZFN) platform established the potential of this approach for the ze...

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Hlavní autoři: Clark, Karl J., Voytas, Daniel F., Ekker, Stephen C.
Médium: Artigo
Jazyk:Inglês
Vydáno: Mary Ann Liebert, Inc. 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174730/
https://ncbi.nlm.nih.gov/pubmed/21929364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/zeb.2011.9993
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