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On-tissue chemical derivatization of 3-methoxysalicylamine for MALDI-imaging mass spectrometry

MALDI-imaging mass spectrometry (IMS) has been shown to be a powerful tool to study drug distributions in organ tissue as well as whole animal bodies. Nevertheless, not all drugs are amenable to MALDI while others may be limited by poor sensitivity poor sensitivity. The use of chemical derivatizatio...

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Detalhes bibliográficos
Main Authors: Chacon, Almary, Zagol-Ikapitte, Irene, Amarnath, Venkataraman, Reyzer, Michelle L., Oates, John A., Caprioli, Richard M., Boutaud, Olivier
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174490/
https://ncbi.nlm.nih.gov/pubmed/21834023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.1958
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