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On-tissue chemical derivatization of 3-methoxysalicylamine for MALDI-imaging mass spectrometry

MALDI-imaging mass spectrometry (IMS) has been shown to be a powerful tool to study drug distributions in organ tissue as well as whole animal bodies. Nevertheless, not all drugs are amenable to MALDI while others may be limited by poor sensitivity poor sensitivity. The use of chemical derivatizatio...

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Главные авторы: Chacon, Almary, Zagol-Ikapitte, Irene, Amarnath, Venkataraman, Reyzer, Michelle L., Oates, John A., Caprioli, Richard M., Boutaud, Olivier
Формат: Artigo
Язык:Inglês
Опубликовано: 2011
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174490/
https://ncbi.nlm.nih.gov/pubmed/21834023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jms.1958
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