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MMP9 deficiency does not decrease blood–brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis

Expression of matrix metalloproteinases (MMPs), especially MMP9 correlates with blood–brain barrier (BBB) disruption during many neuroinflammatory diseases. During neurotropic coronavirus virus (JHMV) induced encephalomyelitis, MMP9 activity is restricted to neutrophils. Furthermore, myeloid cell de...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Savarin, Carine, Stohlman, Stephen A., Rietsch, Anna M., Butchi, Niranjan, Ransohoff, Richard M., Bergmann, Cornelia C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Wiley Subscription Services, Inc., A Wiley Company 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174277/
https://ncbi.nlm.nih.gov/pubmed/21800363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21222
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