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MMP9 deficiency does not decrease blood–brain barrier disruption, but increases astrocyte MMP3 expression during viral encephalomyelitis

Expression of matrix metalloproteinases (MMPs), especially MMP9 correlates with blood–brain barrier (BBB) disruption during many neuroinflammatory diseases. During neurotropic coronavirus virus (JHMV) induced encephalomyelitis, MMP9 activity is restricted to neutrophils. Furthermore, myeloid cell de...

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Detalhes bibliográficos
Main Authors: Savarin, Carine, Stohlman, Stephen A., Rietsch, Anna M., Butchi, Niranjan, Ransohoff, Richard M., Bergmann, Cornelia C.
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174277/
https://ncbi.nlm.nih.gov/pubmed/21800363
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/glia.21222
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