Nrf2, a PPARγ Alternative Pathway to Promote CD36 Expression on Inflammatory Macrophages: Implication for Malaria

CD36 is the major receptor mediating nonopsonic phagocytosis of Plasmodium falciparum-parasitized erythrocytes by macrophages. Its expression on macrophages is mainly controlled by the nuclear receptor PPARγ. Here, we demonstrate that inflammatory processes negatively regulate CD36 expression on hum...

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Detalhes bibliográficos
Main Authors: Olagnier, David, Lavergne, Rose-Anne, Meunier, Etienne, Lefèvre, Lise, Dardenne, Christophe, Aubouy, Agnès, Benoit-Vical, Françoise, Ryffel, Bernhard, Coste, Agnès, Berry, Antoine, Pipy, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174257/
https://ncbi.nlm.nih.gov/pubmed/21949655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002254
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