PPARγ Ligands Switched High Fat Diet-Induced Macrophage M2b Polarization toward M2a Thereby Improving Intestinal Candida Elimination

Obesity is associated with a chronic low-grade inflammation that predisposes to insulin resistance and the development of type 2 diabetes. In this metabolic context, gastrointestinal (GI) candidiasis is common. We recently demonstrated that the PPARγ ligand rosiglitazone promotes the clearance of Ca...

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Main Authors: Lefèvre, Lise, Galès, Amandine, Olagnier, David, Bernad, José, Perez, Laurence, Burcelin, Rémy, Valentin, Alexis, Auwerx, Johan, Pipy, Bernard, Coste, Agnès
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2010
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Research Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2942900/
https://ncbi.nlm.nih.gov/pubmed/20877467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012828
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