PPARγ Controls Dectin-1 Expression Required for Host Antifungal Defense against Candida albicans

We recently showed that IL-13 or peroxisome proliferator activated receptor γ (PPARγ) ligands attenuate Candida albicans colonization of the gastrointestinal tract. Here, using a macrophage-specific Dectin-1 deficient mice model, we demonstrate that Dectin-1 is essential to control fungal gastrointe...

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Detalhes bibliográficos
Main Authors: Galès, Amandine, Conduché, Annabelle, Bernad, José, Lefevre, Lise, Olagnier, David, Béraud, Maryse, Martin-Blondel, Guillaume, Linas, Marie-Denise, Auwerx, Johan, Coste, Agnès, Pipy, Bernard
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
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Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2795865/
https://ncbi.nlm.nih.gov/pubmed/20062524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000714
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