Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin

The Warburg Effect is characterized by an irreversible injury to mitochondrial oxidative phosphorylation (OXPHOS) and an increased rate of aerobic glycolysis. In this study, we utilized a breast epithelial cell line lacking mitochondrial DNA (rho(0)) that exhibits the Warburg Effect associated with...

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Bibliografiske detaljer
Main Authors: Ayyasamy, Vanniarajan, Owens, Kjerstin M., Desouki, Mohamed Mokhtar, Liang, Ping, Bakin, Andrei, Thangaraj, Kumarasamy, Buchsbaum, Donald J., LoBuglio, Albert F., Singh, Keshav K.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2011
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174207/
https://ncbi.nlm.nih.gov/pubmed/21935467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024792
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