Cellular Model of Warburg Effect Identifies Tumor Promoting Function of UCP2 in Breast Cancer and Its Suppression by Genipin

The Warburg Effect is characterized by an irreversible injury to mitochondrial oxidative phosphorylation (OXPHOS) and an increased rate of aerobic glycolysis. In this study, we utilized a breast epithelial cell line lacking mitochondrial DNA (rho(0)) that exhibits the Warburg Effect associated with...

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Detalhes bibliográficos
Main Authors: Ayyasamy, Vanniarajan, Owens, Kjerstin M., Desouki, Mohamed Mokhtar, Liang, Ping, Bakin, Andrei, Thangaraj, Kumarasamy, Buchsbaum, Donald J., LoBuglio, Albert F., Singh, Keshav K.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2011
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174207/
https://ncbi.nlm.nih.gov/pubmed/21935467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024792
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