Human REV3 DNA Polymerase Zeta Localizes to Mitochondria and Protects the Mitochondrial Genome

To date, mitochondrial DNA polymerase γ (POLG) is the only polymerase known to be present in mammalian mitochondria. A dogma in the mitochondria field is that there is no other polymerase present in the mitochondria of mammalian cells. Here we demonstrate localization of REV3 DNA polymerase in the m...

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Bibliographic Details
Published in:PLoS One
Main Authors: Singh, Bhupendra, Li, Xiurong, Owens, Kjerstin M., Vanniarajan, Ayyasamy, Liang, Ping, Singh, Keshav K.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4604079/
https://ncbi.nlm.nih.gov/pubmed/26462070
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0140409
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