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A New Anti-Depressive Strategy for the Elderly: Ablation of FKBP5/FKBP51
The gene FKBP5 codes for FKBP51, a co-chaperone protein of the Hsp90 complex that increases with age. Through its association with Hsp90, FKBP51 regulates the glucocorticoid receptor (GR). Single nucleotide polymorphisms (SNPs) in the FKBP5 gene associate with increased recurrence of depressive epis...
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| Главные авторы: | , , , , , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
Public Library of Science
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3174203/ https://ncbi.nlm.nih.gov/pubmed/21935478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0024840 |
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