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The Hsp90 Cochaperone, FKBP51, Increases Tau Stability and Polymerizes Microtubules

Imbalanced protein load within cells is a critical aspect for most diseases of aging. In particular, the accumulation of proteins into neurotoxic aggregates is a common thread for a host of neurodegenerative diseases. Our previous work demonstrated that age-related changes to the cellular chaperone...

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Main Authors:	Jinwal, Umesh K., Koren, John, Borysov, Sergiy I., Schmid, Andreas B., Abisambra, Jose F., Blair, Laura J., Johnson, Amelia G., Jones, Jeffrey R., Shults, Cody L., O'Leary, John C., Jin, Ying, Buchner, Johannes, Cox, Marc B., Dickey, Chad A.
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Society for Neuroscience 2010
נושאים:	Articles
גישה מקוונת:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2830818/ https://ncbi.nlm.nih.gov/pubmed/20071522 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4815-09.2010
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The Hsp90 Cochaperone, FKBP51, Increases Tau Stability and Polymerizes Microtubules

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