The Disease-Associated Chaperone FKBP51 Impairs Cognitive Function by Accelerating AMPA Receptor Recycling

Increased expression of the FK506-binding protein 5 (FKBP5) gene has been associated with a number of diseases, but most prominently in connection to psychiatric illnesses. Many of these psychiatric disorders present with dementia and other cognitive deficits, but a direct connection between these i...

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Pubblicato in:eNeuro
Autori principali: Blair, Laura J., Criado-Marrero, Marangelie, Zheng, Dali, Wang, Xinming, Kamath, Siddharth, Nordhues, Bryce A., Weeber, Edwin J., Dickey, Chad A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2019
Soggetti:
New Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6450497/
https://ncbi.nlm.nih.gov/pubmed/30963102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/ENEURO.0242-18.2019
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