Targeting the FKBP51/GR/Hsp90 Complex to Identify Functionally Relevant Treatments for Depression and PTSD

Genetic and epigenetic alterations in FK506-binding protein 5 (FKBP5) have been associated with increased risk for psychiatric disorders, including post-traumatic stress disorder (PTSD). Some of these common variants can increase the expression of FKBP5, the gene that encodes FKBP51. Excess FKBP51 p...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:ACS Chem Biol
Main Authors: Sabbagh, Jonathan J., Cordova, Ricardo A., Zheng, Dali, Marrero, Marangelie-Criado, Lemus, Andrea, Li, Pengfei, Baker, Jeremy D., Nordhues, Bryce A., Darling, April L., Martinez-Licha, Carlos, Rutz, Daniel A., Patel, Shreya, Buchner, Johannes, Leahy, James W., Koren, John, Dickey, Chad A., Blair, Laura J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6126901/
https://ncbi.nlm.nih.gov/pubmed/29893552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.8b00454
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados