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Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene

BACKGROUND: Random monoallelic expression contributes to phenotypic variation of cells and organisms. However, the epigenetic mechanisms by which individual alleles are randomly selected for expression are not known. Taking cues from chromatin signatures at imprinted gene loci such as the insulin-li...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Thomas, Brandon J, Rubio, Eric D, Krumm, Niklas, Broin, Pilib Ó, Bomsztyk, Karol, Welcsh, Piri, Greally, John M, Golden, Aaron A, Krumm, Anton
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: BioMed Central 2011
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174113/
https://ncbi.nlm.nih.gov/pubmed/21812971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-4-14
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