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Alignment-free clustering of transcription factor binding motifs using a genetic-k-medoids approach

BACKGROUND: Familial binding profiles (FBPs) represent the average binding specificity for a group of structurally related DNA-binding proteins. The construction of such profiles allows the classification of novel motifs based on similarity to known families, can help to reduce redundancy in motif d...

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Detalles Bibliográficos
Publicado en:BMC Bioinformatics
Autores principales: Broin, Pilib Ó, Smith, Terry J, Golden, Aaron AJ
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4384390/
https://ncbi.nlm.nih.gov/pubmed/25627106
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-015-0450-2
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