Allele-specific transcriptional elongation regulates monoallelic expression of the IGF2BP1 gene

BACKGROUND: Random monoallelic expression contributes to phenotypic variation of cells and organisms. However, the epigenetic mechanisms by which individual alleles are randomly selected for expression are not known. Taking cues from chromatin signatures at imprinted gene loci such as the insulin-li...

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Bibliografiske detaljer
Main Authors: Thomas, Brandon J, Rubio, Eric D, Krumm, Niklas, Broin, Pilib Ó, Bomsztyk, Karol, Welcsh, Piri, Greally, John M, Golden, Aaron A, Krumm, Anton
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2011
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3174113/
https://ncbi.nlm.nih.gov/pubmed/21812971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1756-8935-4-14
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