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Administration of vitamin K does not counteract the ectopic mineralization of connective tissues in Abcc6(−/−) mice, a model for pseudoxanthoma elasticum
Pseudoxanthoma elasticum (PXE) is a heritable multisystem disorder manifesting with ectopic calcification of peripheral connective tissues, caused by mutations in the ABCC6 gene. Alterations in vitamin K metabolism have been suggested to contribute to the pathomechanisms of the mineralization proces...
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| Autori principali: | , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Landes Bioscience
2011
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173996/ https://ncbi.nlm.nih.gov/pubmed/21304270 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.4.14862 |
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