Administration of vitamin K does not counteract the ectopic mineralization of connective tissues in Abcc6(−/−) mice, a model for pseudoxanthoma elasticum

Pseudoxanthoma elasticum (PXE) is a heritable multisystem disorder manifesting with ectopic calcification of peripheral connective tissues, caused by mutations in the ABCC6 gene. Alterations in vitamin K metabolism have been suggested to contribute to the pathomechanisms of the mineralization proces...

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Bibliografiske detaljer
Main Authors: Jiang, Qiujie, Li, Qiaoli, Grand-Pierre, Alix E, Schurgers, Leon J, Uitto, Jouni
Format: Artigo
Sprog:Inglês
Udgivet: Landes Bioscience 2011
Fag:
Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173996/
https://ncbi.nlm.nih.gov/pubmed/21304270
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.10.4.14862
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