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Warfarin Accelerates Ectopic Mineralization in Abcc6(−/−) Mice: Clinical Relevance to Pseudoxanthoma Elasticum
Pseudoxanthoma elasticum (PXE) is a multisystem ectopic mineralization disorder caused by mutations in the ABCC6 gene. Warfarin, a commonly used anticoagulant, is associated with increased mineralization of the arterial blood vessels and cardiac valves. We hypothesized that warfarin may accelerate e...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Investigative Pathology
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3620423/ https://ncbi.nlm.nih.gov/pubmed/23415960 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ajpath.2012.12.037 |
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