Seeking sense of antisense switch transcripts

In B lymphocytes, class switch recombination (CSR) machinery targets highly repetitive sequences, called switch (S) sequences, in the constant domain of the immunoglobulin heavy chain (IgH) locus. Cotranscriptional generation of R loops at S sequences provides the substrate for the mutagenic enzyme...

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Main Authors: Haddad, Dania, Puget, Nadine, Laviolette-Malirat, Nathalie, Conte, Caroline, Khamlichi, Ahmed Amine
Formato: Artigo
Idioma:Inglês
Publicado: Landes Bioscience 2011
Assuntos:
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173686/
https://ncbi.nlm.nih.gov/pubmed/21922061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/trns.2.4.16784
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