Evaluation of the effect of dapagliflozin on cardiac repolarization: a thorough QT/QTc study

INTRODUCTION: Dapagliflozin is a first-in-class sodium-glucose transporter 2 (SGLT2) inhibitor under investigation for the treatment of type 2 diabetes mellitus. A thorough QTc study was conducted, according to International Conference on Harmonization E14 guidelines, to characterize the effect of d...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Carlson, Glenn F., Tou, Conrad K. P., Parikh, Shamik, Birmingham, Bruce K., Butler, Kathleen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Springer Healthcare Communications 2011
Pynciau:
Original Research
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173598/
https://ncbi.nlm.nih.gov/pubmed/22127822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13300-011-0003-2
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