Autocrine activity of soluble Flt-1 controls endothelial cell function and angiogenesis

BACKGROUND: The negative feedback system is an important physiological regulatory mechanism controlling angiogenesis. Soluble vascular endothelial growth factor (VEGF) receptor-1 (sFlt-1), acts as a potent endogenous soluble inhibitor of VEGF- and placenta growth factor (PlGF)-mediated biological fu...

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Autores principales: Ahmad, Shakil, Hewett, Peter W, Al-Ani, Bahjat, Sissaoui, Samir, Fujisawa, Takeshi, Cudmore, Melissa J, Ahmed, Asif
Formato: Artigo
Lenguaje:Inglês
Publicado: BioMed Central 2011
Materias:
Research
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173355/
https://ncbi.nlm.nih.gov/pubmed/21752276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-824X-3-15
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