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Bioenergetic effects of hydrogen sulfide suppress soluble Flt-1 and soluble endoglin in cystathionine gamma-lyase compromised endothelial cells

Endothelial dysfunction is a hallmark of preeclampsia, a life-threatening complication of pregnancy characterised by hypertension and elevated soluble Fms-Like Tyrosine Kinase-1 (sFlt-1). Dysregulation of hydrogen sulfide (H(2)S) by inhibition of cystathionine γ-lyase (CSE) increases sFlt-1 and solu...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Sanchez-Aranguren, Lissette Carolina, Ahmad, Shakil, Dias, Irundika H. K., Alzahrani, Faisal A., Rezai, Homira, Wang, Keqing, Ahmed, Asif
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7519095/
https://ncbi.nlm.nih.gov/pubmed/32978411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-72371-2
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