Reduction of circulating soluble Flt-1 alleviates preeclampsia-like symptoms in a mouse model

Preeclampsia (PE) is characterized by widespread endothelial damage with hypertension, proteinuria, glomeruloendotheliosis and elevated soluble Flt-1 (sFlt-1), a natural occurring antagonist of vascular endothelial growth factor (VEGF). Cancer patients receiving anti-VEGF therapy exhibit similar sym...

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Bibliografiske detaljer
Main Authors: Bergmann, Astrid, Ahmad, Shakil, Cudmore, Melissa, Gruber, Achim D, Wittschen, Petra, Lindenmaier, Werner, Christofori, Gerhard, Gross, Volkmar, Gonzalves, Andrey Ch da Costa, Gröne, Hermann-Josef, Ahmed, Asif, Weich, Herbert A
Format: Artigo
Sprog:Inglês
Udgivet: Blackwell Publishing Ltd 2010
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Original Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3829045/
https://ncbi.nlm.nih.gov/pubmed/19538465
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2009.00820.x
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