Distinct Involvement of the Gab1 and Grb2 Adaptor Proteins in Signal Transduction by the Related Receptor Tyrosine Kinases RON and MET

Although the signal transduction mechanisms of the receptor tyrosine kinase MET are well defined, less is known about its close relative RON. MET initiates intracellular signaling by autophosphorylation on specific cytoplasmic tyrosines that form docking sites for the adaptor proteins Grb2 and Gab1....

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Hlavní autoři: Chaudhuri, Amitabha, Xie, Ming-Hong, Yang, Becky, Mahapatra, Kaushiki, Liu, Jinfeng, Marsters, Scot, Bodepudi, Sweta, Ashkenazi, Avi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Biochemistry and Molecular Biology 2011
Témata:
Signal Transduction
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173233/
https://ncbi.nlm.nih.gov/pubmed/21784853
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.239384
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