Anti-apoptotic Role of Caspase-cleaved GAB1 Adaptor Protein in Hepatocyte Growth Factor/Scatter Factor-MET Receptor Protein Signaling

The GRB2-associated binder 1 (GAB1) docking/scaffold protein is a key mediator of the MET-tyrosine kinase receptor activated by hepatocyte growth factor/scatter factor (HGF/SF). Activated MET promotes recruitment and tyrosine phosphorylation of GAB1, which in turn recruits multiple proteins and medi...

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Detalhes bibliográficos
Main Authors: Le Goff, Arnaud, Ji, Zongling, Leclercq, Bérénice, Bourette, Roland P., Mougel, Alexandra, Guerardel, Cateline, de Launoit, Yvan, Vicogne, Jérôme, Goormachtigh, Gautier, Fafeur, Véronique
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3471683/
https://ncbi.nlm.nih.gov/pubmed/22915589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.409797
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