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The Adaptor Protein soc-1/Gab1 Modifies Growth Factor Receptor Output in Caenorhabditis elegans
Previous genetic analysis has shown that dos/soc-1/Gab1 functions positively in receptor tyrosine kinase (RTK)-stimulated Ras/Map kinase signaling through the recruitment of csw/ptp-2/Shp2. Using sensitized assays in Caenorhabditis elegans for let-23/Egfr and daf-2/InsR (insulin receptor-like) signa...
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| Format: | Artigo |
| Langue: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1461424/ https://ncbi.nlm.nih.gov/pubmed/16547100 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.055822 |
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