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Homologous Recombination Is Required for Genome Stability in the Absence of DOG-1 in Caenorhabditis elegans
In C. elegans, DOG-1 prevents deletions that initiate in polyG/polyC tracts (G/C tracts), most likely by unwinding secondary structures that can form in G/C tracts during lagging-strand DNA synthesis. We have used the dog-1 mutant to assay the in vivo contribution of various repair genes to the main...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
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Copyright © 2006 by the Genetics Society of America
2006
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| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1526509/ https://ncbi.nlm.nih.gov/pubmed/16547095 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.106.056879 |
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