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Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

Autophagy has been recently demonstrated to control cell and tissue homeostasis, including the functions of various metabolic tissues. However, it remains unclear whether autophagy is critical for the central nervous system and particularly the hypothalamus for exerting metabolic regulation. Using a...

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Bibliografiset tiedot
Päätekijät: Meng, Qingyuan, Cai, Dongsheng
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2011
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173166/
https://ncbi.nlm.nih.gov/pubmed/21784844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254417
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