Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

Autophagy has been recently demonstrated to control cell and tissue homeostasis, including the functions of various metabolic tissues. However, it remains unclear whether autophagy is critical for the central nervous system and particularly the hypothalamus for exerting metabolic regulation. Using a...

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Bibliographic Details
Main Authors: Meng, Qingyuan, Cai, Dongsheng
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Metabolism
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173166/
https://ncbi.nlm.nih.gov/pubmed/21784844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254417
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