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Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

Autophagy has been recently demonstrated to control cell and tissue homeostasis, including the functions of various metabolic tissues. However, it remains unclear whether autophagy is critical for the central nervous system and particularly the hypothalamus for exerting metabolic regulation. Using a...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Meng, Qingyuan, Cai, Dongsheng
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2011
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173166/
https://ncbi.nlm.nih.gov/pubmed/21784844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254417
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