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Defective Hypothalamic Autophagy Directs the Central Pathogenesis of Obesity via the IκB Kinase β (IKKβ)/NF-κB Pathway

Autophagy has been recently demonstrated to control cell and tissue homeostasis, including the functions of various metabolic tissues. However, it remains unclear whether autophagy is critical for the central nervous system and particularly the hypothalamus for exerting metabolic regulation. Using a...

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Detalhes bibliográficos
Main Authors: Meng, Qingyuan, Cai, Dongsheng
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173166/
https://ncbi.nlm.nih.gov/pubmed/21784844
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.254417
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