Molecular Mechanism Underlying 1,25-Dihydroxyvitamin D Regulation of Nephrin Gene Expression

Nephrin plays a key role in maintaining the structure of the slit diaphragm in the glomerular filtration barrier. Our previous studies have demonstrated potent renoprotective activity for 1,25-dihydroxyvitamin D (1,25(OH)(2)D(3)). Here we showed that in podocytes 1,25(OH)(2)D(3) markedly stimulated...

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Bibliografiske detaljer
Main Authors: Deb, Dilip K., Wang, Youli, Zhang, Zhongyi, Nie, Hongguang, Huang, Xueshi, Yuan, Zhengwei, Chen, Yunzi, Zhao, Qun, Li, Yan Chun
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Gene Regulation
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173158/
https://ncbi.nlm.nih.gov/pubmed/21803771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.269118
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