1,25-Dihydroxyvitamin D(3) Suppresses Inflammation-Induced Expression of Plasminogen Activator Inhibitor-1 by Blocking Nuclear Factor-κB Activation

Plasminogen activator inhibitor (PAI)-1 is a major fibrinolytic inhibitor. High PAI-1 is associated with increased renal and cardiovascular disease risk. Previous studies demonstrated PAI-1 down-regulation by 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), but the molecular mechanism remains unknown....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Chen, Yunzi, Kong, Juan, Sun, Tao, Li, George, Szeto, Frances L., Liu, Weicheng, Deb, Dilip K., Wang, Youli, Zhao, Qun, Thadhani, Ravi, Li, Yan Chun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3049452/
https://ncbi.nlm.nih.gov/pubmed/21176770
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.12.020
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