Učitavanje...
1,25-Dihydroxyvitamin D(3) Suppresses Inflammation-Induced Expression of Plasminogen Activator Inhibitor-1 by Blocking Nuclear Factor-κB Activation
Plasminogen activator inhibitor (PAI)-1 is a major fibrinolytic inhibitor. High PAI-1 is associated with increased renal and cardiovascular disease risk. Previous studies demonstrated PAI-1 down-regulation by 1,25-dihydroxyvitamin D(3) (1,25(OH)(2)D(3)), but the molecular mechanism remains unknown....
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| Glavni autori: | , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2010
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| Teme: | |
| Online pristup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3049452/ https://ncbi.nlm.nih.gov/pubmed/21176770 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.abb.2010.12.020 |
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