Amyloid β Peptide-(1–42) Induces Internalization and Degradation of β(2) Adrenergic Receptors in Prefrontal Cortical Neurons

Emerging evidence indicates that amyloid β peptide (Aβ) initially induces subtle alterations in synaptic function in Alzheimer disease. We have recently shown that Aβ binds to β(2) adrenergic receptor (β(2)AR) and activates protein kinase A (PKA) signaling for glutamatergic regulation of synaptic ac...

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Detaylı Bibliyografya
Asıl Yazarlar: Wang, Dayong, Yuen, Eunice Y., Zhou, Yuan, Yan, Zhen, Xiang, Yang K.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2011
Konular:
Signal Transduction
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173113/
https://ncbi.nlm.nih.gov/pubmed/21757762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244335
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