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Binding of amyloid β peptide to β(2) adrenergic receptor induces PKA-dependent AMPA receptor hyperactivity
Progressive decrease in neuronal function is an established feature of Alzheimer’s disease (AD). Previous studies have shown that amyloid β (Aβ) peptide induces acute increase in spontaneous synaptic activity accompanied by neurotoxicity, and Aβ induces excitotoxic neuronal death by increasing calci...
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| Главные авторы: | , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Federation of American Societies for Experimental Biology
2010
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2923357/ https://ncbi.nlm.nih.gov/pubmed/20395454 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.10-156661 |
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