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Amyloid β Peptide-(1–42) Induces Internalization and Degradation of β(2) Adrenergic Receptors in Prefrontal Cortical Neurons
Emerging evidence indicates that amyloid β peptide (Aβ) initially induces subtle alterations in synaptic function in Alzheimer disease. We have recently shown that Aβ binds to β(2) adrenergic receptor (β(2)AR) and activates protein kinase A (PKA) signaling for glutamatergic regulation of synaptic ac...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
American Society for Biochemistry and Molecular Biology
2011
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3173113/ https://ncbi.nlm.nih.gov/pubmed/21757762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.244335 |
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