Nucleotides and Phosphorylation Bi-directionally Modulate Ca(2+)/Calmodulin-dependent Protein Kinase II (CaMKII) Binding to the N-Methyl-d-aspartate (NMDA) Receptor Subunit GluN2B

The Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII) and the NMDA-type glutamate receptor are key regulators of synaptic plasticity underlying learning and memory. Direct binding of CaMKII to the NMDA receptor subunit GluN2B (formerly known as NR2B) (i) is induced by Ca(2+)/CaM but outla...

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Detalhes bibliográficos
Main Authors: O'Leary, Heather, Liu, Wallace H., Rorabaugh, Jacki M., Coultrap, Steven J., Bayer, K. Ulrich
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Neurobiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3173099/
https://ncbi.nlm.nih.gov/pubmed/21768120
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.233668
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