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DAPK1 mediates LTD by making CaMKII/GluN2B binding LTP-specific

The death associated protein kinase 1 (DAPK1) is a potent mediator of neuronal cell death. Here, we find that DAPK1 also functions in synaptic plasticity by regulating the Ca(2+)/calmodulin (CaM)-dependent protein kinase II (CaMKII). CaMKII and T286-autophosphorylation are required for both long-ter...

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Bibliografske podrobnosti
izdano v:Cell Rep
Main Authors: Goodell, Dayton J., Zaegel, Vincent, Coultrap, Steven J., Hell, Johannes W., Bayer, K. Ulrich
Format: Artigo
Jezik:Inglês
Izdano: 2017
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549467/
https://ncbi.nlm.nih.gov/pubmed/28614711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.05.068
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