Deletion of the metabolic transcriptional coactivator PGC1β induces cardiac arrhythmia

AIMS: Peroxisome proliferator-activated receptor-γ coactivators PGC1α and PGC1β modulate mitochondrial biogenesis and energy homeostasis. The function of these transcriptional coactivators is impaired in obesity, insulin resistance, and type 2 diabetes. We searched for transcriptomic, lipidomic, and...

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Detalhes bibliográficos
Main Authors: Gurung, Iman S., Medina-Gomez, Gema, Kis, Adrienn, Baker, Michael, Velagapudi, Vidya, Neogi, Sudeshna Guha, Campbell, Mark, Rodriguez-Cuenca, Sergio, Lelliott, Christopher, McFarlane, Ian, Oresic, Matej, Grace, Andrew A., Vidal-Puig, Antonio, Huang, Christopher L.-H.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2011
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Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172981/
https://ncbi.nlm.nih.gov/pubmed/21632884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/cvr/cvr155
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