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Adaptation and failure of pancreatic β cells in murine models with different degrees of metabolic syndrome
The events that contribute to the expansion of β-cell mass and enhanced β-cell function in insulin-resistant states have not been elucidated fully. Recently, we showed that β-cell adaptation failed dramatically in adult, insulin-resistant POKO mice, which contrasts with the appropriate expansion of...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The Company of Biologists Limited
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2773727/ https://ncbi.nlm.nih.gov/pubmed/19841237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.003251 |
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