Accelerated renal disease is associated with the development of metabolic syndrome in a glucolipotoxic mouse model

Individuals with metabolic syndrome are at high risk of developing chronic kidney disease (CKD) through unclear pathogenic mechanisms. Obesity and diabetes are known to induce glucolipotoxic effects in metabolically relevant organs. However, the pathogenic role of glucolipotoxicity in the aetiology...

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Detalhes bibliográficos
Main Authors: Martínez-García, Cristina, Izquierdo, Adriana, Velagapudi, Vidya, Vivas, Yurena, Velasco, Ismael, Campbell, Mark, Burling, Keith, Cava, Fernando, Ros, Manuel, Orešič, Matej, Vidal-Puig, Antonio, Medina-Gomez, Gema
Formato: Artigo
Idioma:Inglês
Publicado em: The Company of Biologists Limited 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424461/
https://ncbi.nlm.nih.gov/pubmed/22773754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dmm.009266
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