Analysis of the Ketosynthase-Chain Length Factor Heterodimer from the Fredericamycin Polyketide Synthase

The pentadecaketide fredericamycin has the longest carbon chain backbone among polycyclic aromatic polyketide antibiotics whose biosynthetic genes have been sequenced. This backbone is synthesized by the bimodular fdm polyketide synthase (PKS). The initiation module is thought to synthesize a C(6) i...

Full description

Saved in:
Bibliographic Details
Main Authors: Szu, Ping-Hui, Govindarajan, Sridhar, Meehan, Michael J., Das, Abhirup, Nguyen, Don D., Dorrestein, Pieter C., Minshull, Jeremy, Khosla, Chaitan
Format: Artigo
Language:Inglês
Published: 2011
Subjects:
Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172819/
https://ncbi.nlm.nih.gov/pubmed/21867917
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2011.07.015
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items