Reproductive capacity in iron overloaded women with thalassemia major

The pathophysiology of iron-induced compromised fertility in women with thalassemia major (TM) was evaluated in 26 adult TM females. Low gonadotropin secretion resulted in reduced ovarian antral follicle count and ovarian volume, but levels of anti-müllerian hormone (AMH), a sensitive marker for ova...

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Bibliographic Details
Main Authors: Singer, Sylvia T., Vichinsky, Elliott P., Gildengorin, Ginny, van Disseldorp, Jereon, Rosen, Mitchell, Cedars, Marcelle I.
Format: Artigo
Language:Inglês
Published: American Society of Hematology 2011
Subjects:
Red Cells, Iron, and Erythropoiesis
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172803/
https://ncbi.nlm.nih.gov/pubmed/21757620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-06-360271
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