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Inhibition of heme oxygenase ameliorates anemia and reduces iron overload in a β-thalassemia mouse model

Thalassemias are a heterogeneous group of red blood cell disorders, considered a major cause of morbidity and mortality among genetic diseases. However, there is still no universally available cure for thalassemias. The underlying basis of thalassemia pathology is the premature apoptotic destruction...

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Detalhes bibliográficos
Publicado no:Blood
Main Authors: Garcia-Santos, Daniel, Hamdi, Amel, Saxova, Zuzana, Fillebeen, Carine, Pantopoulos, Kostas, Horvathova, Monika, Ponka, Prem
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5757685/
https://ncbi.nlm.nih.gov/pubmed/29180398
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2017-07-798728
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