Differential niche and Wnt requirements during acute myeloid leukemia progression

Hematopoietic stem cells (HSCs) engage in complex bidirectional signals with the hematopoietic microenvironment (HM), and there is emerging evidence that leukemia stem cells (LSCs) may use similar interactions. Using a syngeneic retroviral model of MLL-AF9 induced acute myeloid leukemia (AML), we ha...

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Détails bibliographiques
Auteurs principaux: Lane, Steven W., Wang, Yingzi J., Lo Celso, Cristina, Ragu, Christine, Bullinger, Lars, Sykes, Stephen M., Ferraro, Francesca, Shterental, Sebastian, Lin, Charles P., Gilliland, D. Gary, Scadden, David T., Armstrong, Scott A., Williams, David A.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2011
Sujets:
Myeloid Neoplasia
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3172801/
https://ncbi.nlm.nih.gov/pubmed/21765021
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-03-345165
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